Notes for macOS users
Access to folders
In recent macOS versions, the operating system will ask if you want to give FS-UAE / FS-UAE Launcher / FS-UAE Arcade access to your Documents folder. If you answer no to this question, FS-UAE will fail to start, and you will not get the question again. In this case, go to "System Preferences" -> "Security & Privacy" -> "Privacy" tab -> "Files and Folders" and check the box(es) giving FS-UAE access to "Documents Folder".
Fullscreen mode does not use an OS X fullscreen spaces by default, but you can enable this with the following environment variable:
SDL_VIDEO_MAC_FULLSCREEN_SPACES = 1
You can specify this in FS-UAE Launcher Settings: Advanced Settings. Remember to write it as shown above in all caps.
In order to see individual mouse devices, you may have to go to Preferences -> Security & Privacy -> Input Monitoring, and allow access for FS-UAE, FS-UAE Launcher and FS-UAE Arcade.